Our new Crystal clear+ tissue clearing system is the only approach that delipidates samples with no adjust in morphology and with negligible influence on structural integrity.
Megatome is a vibrating microtome made to area a wide choice of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With superior blade vibrating frequency and minimized blade deflection, Megatome enables high-throughput tissue sectioning with uniform surface profile, along with nominal tissue hurt and knowledge decline.
Antibodies might consider weeks to diffuse via only a few millimeters of tissue, with a steep labeling gradient from surface to core.
Megatome is designed for precision: the blade vibrates at the next frequency and bigger amplitude vary than other microtomes, and encompasses a special deflection Command mechanism.
Clone the challenge or grab the most up-to-date release. Jogging the utility will range a bit depending on the way you retrieve the job.
Our preformulated EasyIndex Resolution raises and homogenize the refractive index of delipidated tissue samples, rendering them completely transparent. This allows gentle penetration to the sample and guarantees the acquisition of high-resolution, in-aim impression info.
Megatome is a novel microtome that enables for high-precision sectioning of megatomi.com a variety of tissue samples – from organoids, to arrays of animal organs, to intact human brain hemispheres – with minimal tissue problems and information decline.
It’s the perfect time to update your microtome to Megatome. With accurate significant-frequency slicing for an unmatched array of sample dimensions and types – from organoids and tumors to expanded tissues, sample arrays, and intact primate organs – Megatome is optimized for varied programs.
Fully delipidate complete mouse brains or comparably sized samples in only one day with SmartBatch+, or in a single week with our passive clearing package.
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Our novel Defend tissue preservation strategy varieties intramolecular bonds applying polyfunctional, flexible epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.